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Glyburide is added to metformin in therapy of a 66-year-old man in treatment of type 2 diabetes mellitus. The patient should be counseled that which of the following is the most likely adverse effect?
A 40-year-old non-obese male has been running blood pressures averaging 165/108 mmHg despite treatment with atenolol (a beta blocker), amlodipine (a calcium channel blocker) and enalapril (an ACE inhibitor). His serum potassium is 3.0 mg/dL. Which of the following diagnoses is the most likely cause of these findings?
A 77-year-old woman has the acute onset of palpitations. Atrial fibrillation is diagnosed upon electrocardiography. Which of the following is the most likely underlying cause?
A 55-year-old woman has a 3 month history of worsening constipation, cold intolerance, dry skin and forgetfulness. Examination shows dry skin, periorbital edema and slow relaxation of deep tendon reflexes. Which of the following is the most likely electrocardiographic abnormality to be noted in the patient?
A 62-year-old woman has marked lightheadedness when arising from bed. Sitting blood pressure is 114/74 mm Hg sitting with pulse rate of 80/min. Standing blood pressure is 86/52 mm Hg and pulse rate is 106/min. Which of the following is the most likely diagnosis?
A 40-year-old man has a 2 month history of easy bruising, weight gain, and purple rash on his abdomen. Blood pressure 146/94 mm Hg. Examination shows a round face with central obesity. Depressed purple striae are noted on the abdominal wall. A high dose dexamethasone suppression test shows decreased ACTH and increased cortisol. Which of the following is the most likely diagnosis?
A 52-year-old woman has a 3 month history of cold intolerance, forgetfulness, constipation, and dry skin. Hypothyroidism is diagnosed. Which of the following is the most likely sign to be noted upon examination?
A 61-year-old woman has newly diagnosed hypothyroidism caused by Hashimoto’s thyroiditis. Which of the following is the most likely sign to be noted upon examination?
A 65-year-old woman has a 2 month history of anorexia, nausea, and 5 pound weight loss. Blood pressure, sitting, 100/70 mm Hg with pulse 88/min. Blood pressure, standing, 86/66 mm Hg with pulse 102/min. Examination shows generalized hyperpigmentation. Serum sodium is 126 mEq/L. Which of the following is the preferred initial diagnostic test?
A 61-year-old man has a 2 month history of anorexia, nausea, and 5 pound weight loss. Blood pressure, sitting, 100/70 mm Hg with pulse 88/min. Blood pressure, standing, 86/66 mm Hg with pulse 102/min. Examination shows hyperpigmentation of skin creases. Serum sodium is 126 mEq/L. Which of the following is the most likely laboratory value to be noted?
A 63-year-old diabetic male presents complaining of blurred vision, weakness, nausea, vomiting, and abdominal pain. Physical exam reveals deep, gasping respirations, tachycardia, and orthostatic blood pressure changes. Lab work reveals a random glucose of 620 and a metabolic acidosis. What is the first step in the management of this patient?
A 61-year-old man has diabetic autonomic neuropathy manifest by orthostatic hypotension. Which of the following is the preferred initial therapy?
A 47-year-old woman has newly diagnosed Cushing’s disease. Which of the following signs is least likely to be noted upon examination?
A 58-year-old patient is being treated with long-term glucocorticoid therapy for rheumatoid arthritis. He stopped taking the medicine because he was “feeling better”. He now presents with weakness, fatigue, abdominal pain, severe nausea & vomiting, and altered mental status. Lab findings reveal hyponatremia and hyperkalemia. Which of the following is the most likely diagnosis?
The presence of which of the following differentiates central diabetes insipidus from nephrogenic diabetes insipidus?
Euvolemic hyponatremia is associated with:
Which of the following is contraindicated in the initial management of thyroid storm?
Which of the following is not found in painless thyroiditis?
The physical examination of a 29-year-old asymptomatic euthyroid man shows a solitary, firm, nontender, fixed thyroid nodule. Which of the following is the best diagnostic test?
Which of the following statements concerning type 1 diabetes mellitus is true?
Which of the following diseases is characterized by a severe hypochromic microcytic anemia, marked hepatosplenomegaly, pathologic fractures, and the facial deformities of a prominent forehead and maxilla?
Which of the following is not a consideration when giving thyroid replacement hormone therapy?
Which of the following is a characteristic of diabetic proliferative retinopathy?
Which of the following statements concerning the syndrome of inappropriate antidiuretic hormone is true?
Thyroiditis of the Hashimoto’s type should be considered in the setting of which of the following laboratory findings?
Which of the following is the most reliable method of diagnosing malignant thyroid nodules?
Which of the following statements concerning thyroid nodules is true?
Which of the following statements is correct concerning osteoporosis?
All of the following statements concerning Addison’s disease are true except?
A 56-year-old man complains of frequent headaches and visual disturbances. Physical examination discloses blood pressure of 132/80 and decreased bitemporal visual fields. Which of the following is the best diagnostic study to confirm the diagnosis?